Systemic Lupus & Vasculitis

1.An young female of 25 years comes with h/o of rashes, fever, arthralgia, butterfly rash on face with sparing of naso labial furrow. On examination patient had anemia, mouth ulcers, alopecia, lab investigations positive for ANA antibodies with Leukopenia and Thrombocytopenia

• a) what is your Diagnosis. what are the other features required to diagnose this condition
• b) What is the etiopathology of this diagnosis
• c) what are the other necessary investigations required to confirm and treat this diagnosis
• d) What is the treatment for the above diagnosis
• e) What are the complications you can expect

2.A 28-year-old lady is diagnosed to have Systemic Lupus Erythematosus

• a) Describe the clinical features of this condition
• b) What are the investigations needed to confirm the diagnosis
• c) What is the treatment of this condition

3.20 year old female came with history of fever and joint pains since 2 weeks. On examination, she had splenomegaly and tenderness over knee and sacroiliac joints. She had a skin rash on nose and cheeks.  What is your probable diagnosis  What are the other causes of this presentation  How do you confirm the diagnosis  How do you treat the most probable condition

4.A 20 years young female presented with history of fever, poly arthralgia, facial puffiness, pedal edema and decreased urine output. On examination she has malar rash over the cheek, anasarca and B.P. 150/100 mm Hg. Answer the following.  What is your likely diagnosis  How will you confirm the diagnosis  How will you treat the disease  What are the complications of the disease

5.40 years old male presents with generalized anasarca and decreased urine output for one month. On examination BP 120/80. Proteinurea of 3.5 gm/24 hours and serum albumin 2 gm%. Answer the following: • What is the likely diagnosis. • How do you investigate this patient. • What differential diagnosis will you consider. • How are you going to treat this patient

1.Eosinophilic granulomatosis with Polyangitis

1.ANA and its significance

2.Mention criteria for diagnosis of systemic lupus erythematosus

3.What are antiphospholipid antibodies (APLA). Enumerate four clinical features of APLA syndrome

4.Complications of analgesics

1.Which is the specific test for this disease

• a) Anti CCP abs
• b) Anti RA abs
• c) ANA
• d) Anti dS abs