Bone Tumours

1.Classify bone tumours. Discuss gross and microscopy of osteogenic sarcoma. Add a note on radiological features

2.Classify bone tumors. Describe the etiopathogenesis and clinico-pathological features of osteosarcoma

3.Classify bone tumors. Describe the gross (including x-ray appearances) and microscopic features of the most common malignant bone tumor

1.Describe the genetic basis, radiological findings and morphology of Ewing Sarcoma

2.Osteogenic sarcoma – Aetiopathogenesis and morphology

3.Osteosarcoma

4.A 45-year-old male presents with a swelling over the right knee joint of three months duration. X-Ray reveals an expansile lytic lesion, predominantly in the epiphyseal region of right lower femur without any cortical breach. What is the likely diagnosis and why Describe the radiological, gross and microscopic findings in this condition

1.Osteosarcoma

2.Osteoclastoma

3.Radiologic and morphological features of osteogenic sarcoma

4.Radiologic features and morphology of osteosarcoma

1.Osteoclastoma

2.Ewing’s sarcoma Answer in single sentence: (4x½=2)

3.Osteoclastoma Answer in single sentence: (4x½=2)

4.Name four conditions associated with development of osteosarcoma

1.Small blue round cell tumours include

• 1) Retinoblastoma
• 2) Ewing’s sarcoma 3) Cholangiocarcinoma
• 4) Neuroblastoma
• a) 1, 2 and 3 are correct
• b) 2, 3 and 4 are correct
• c) 1, 3 and 4 are correct
• d) 1, 2 and 4 are correct