Gastric Pathology

1.Classify tumors of stomach. Describe the etiopathogenesis of carcinoma stomach. Describe the gross and microscopic features of carcinoma stomach and explain its modes of spread

1.A 60-year-old male, previously diagnosed with chronic gastritis, presented with weakness, burning sensation on the tongue and numbness of the fingers. On examination he had pallor and patchy red areas on the tongue. His had a haemoglobin of 8gm/dl and MCV of 110fl.

• a) What is the most likely diagnosis
• b) What is the etiopathogenesis of this condition
• c) What are the other laboratory findings seen with this diagnosis

2.50 years male presented with dysphagia since six months. Endoscopy revealed an elevated mass in the antrum with heaped up borders and central ulceration. Clinically left supra clavicular lymphadenopathy. Answer the following  What is your diagnosis.  Discuss the pathogenesis and morphology of the lesion with your diagnosis

3.Causes and morphology of acute and chronic gastric ulcers

4.A 49 years old male complaints of abdominal pain after taking food. He has a previous history of hematemesis. Answer the following • Indicate two differential diagnosis in this patient • Mention the diagnostic test which may be useful in this patient • Enumerate two etiological factors that can be implicated in this case • Discuss briefly the progress of this disease, if untreated

1.Etiopathogenesis of peptic ulcer

2.Helicobacter pylori gastritis

1.What is the stain for H. pylori

2.What is Linitis Plastica

3.Helicobacter pylori associated lesions

4.Define early gastric cancer

5.Factors influencing H pylori virulence

1.Features of Helicobacter pylori infection

• 1) It produces antral gastritis
• 2) It releases ammonia from endogenous urea
• 3) It invades the gastric mucosa
• 4) Warthin starry stain is used to demonstrate it
• a) 1, 2 and 3 are correct
• b) 2, 3 and 4 are correct
• c) 1, 3 and 4 are correct
• d) 1, 2 and 4 are correct