Intestinal Pathology

1.Classification of intestinal polyps

2.Intestinal polyps: classification and syndromes

3.Discuss the types of ulcers in intestine (large and small intestine)

4.Differences between Crohn disease and Ulcerative colitis

5.Discuss the etiopathogenesis of carcinoma colon with a note on the adenoma- carcinoma sequence

6.A 65-year old male presented with change in bowel habits, loss of weight, loss of appetite, weakness, and malaise since one year. After an endoscopic biopsy of the colon, left hemicolectomy was done. Answer the following.  What is the clinical diagnosis.  Describe the etiology and morphology of the lesion.  Molecular mechanism

7.A 72 years old male presented with changes in the bowel habit, bleeding per rectum, loss of weight, fatigue and weakness of six months duration. After endoscopic biopsy of colon, a left sided hemicolectomy was done. Answer the following: • What is the probable diagnosis. • Describe the etiopathogenesis. • Describe the gross and microscopic features of the resected colon • Mention the serological marker which is increased

1.Compare and contrast four important microscopic features of Crohn’s disease and Ulcerative Colitis

2.Differentiate between ulcerative colitis and crohn’s disease

3.Aetiopathogenesis of carcinoma colon

4.Morphology of ulcerative colitis

5.Polyps of intestine

6.Inflammatory bowel disease

7.Microscopic features to distinguish Crohn disease from ulcerative colitis

8.Morphology of Crohns disease

9.Etiopathogenesis of ulcerative colitis

1.Microscopic picture of amoebic dysentery colon

2.Name the common molecular abnormality in carcinoma colon

3.What is Peutz Jegher’s polyp

4.Crohn’s disease Answer in single sentence: (4x½=2)

5.Precancerous lesion of intestine

6.Gross and microscopy of ulcerative colitis

1.(A) Prophylactic colectomy is to be done in all patients with Familial Adenomatous Polyposis (FAP) (R) Minimum 100 polyps are necessary for the diagnosis of FAP

• a) Both A & R are correct and R is the reason for A
• b) Both A & R are correct but R is not reason for A
• c) A is correct R is incorrect
• d) A is incorrect R is correct

2.Risk factors of colorectal adenocarcinoma includes

• 1) Familial adenomatous polyp
• 2) Obesity
• 3) Low fiber diet
• 4) Intestinal amoebiasis
• a) 1, 2, 3
• b) 2, 3, 4
• c) 3, 4, 1
• d) 1, 2, 4