Transplant & Rejection

1.Discuss in detail the mechanism of recognition and rejection of allografts. Add a note on morphology of kidney in various types of rejection

1.Immunological basis of transplant rejection

1.Type I diabetes mellitus

• 1) Associated with HLADR3, HLADR4 or both
• 2) Autoimmune destruction of β cells occurs
• 3) Most common in childhood
• 4) Associated with central obesity
• a) 1, 2 and 3 are correct
• b) 2, 3 and 4 are correct
• c) 1, 3 and 4 are correct
• d) 1, 2 and 4 are correct