Acute Inflammation

1.Write the Cellular events of acute inflammation

2.Define acute inflammation. Discuss vascular changes and cellular events of acute inflammation. Write two beneficial effect of acute inflammation

3.25 year old female presented with acute abdominal pain. On laparotomy the appendix was red and swollen.

• a) What is the most probable diagnosis
• b) Discuss the vascular events of the underlying pathology

4.What are the three components of acute inflammation. Describe the mechanism of intracellular destruction of bacteria

5.Enumerate three major components of acute inflammation. Discuss in detail vascular events in acute inflammation. Add a note on endothelial and leucocyte adhesion molecules

6.Define inflammation. Explain the sequential vascular changes in acute inflammation. What are the outcomes of acute inflammation

1.Chemotaxis

1.Steps involved in phagocytosis with help of a diagram

2.Chemical mediators of acute inflammation

3.Transudate and exudate

1.Differences between exudate and transudate

2.Cytokines involved in acute inflammation

3.Chemotaxis Answer in single sentence: (4x½=2)

4.Define chemotaxis

5.What is an abscess

1.Nitric Oxide is synthesized by

• 1) Neurons
• 2) Endothelial cells
• 3) Hepatocytes
• 4) Monocytes.
• a) 1, 2 and 3 are correct
• b) 2, 3 and 4 are correct
• c) 1, 3 and 4 are correct
• d) 1, 2 and 4 are correct

2.One of the following cytokine is a powerful chemo attractant

• a) Interleukin -8
• b) Interleukin -2
• c) Interleukin -6
• d) Interleukin -4

3.Release of which of the following chemical mediators is most likely responsible for this finding

• a) Nitric oxide
• b) Prostaglandin E2
• c) Complement C3b
• d) Histamine