Renal Tumours

1.Paraneoplastic syndromes

2.60 years old male having fever, weight loss presented with painless hematuria, flank pain, palpable mass left renal angle. C.T. scan confirmed a specific organ mass lesion. Regional lymph nodes and renal vein involvement. Chest radiography shows cannon ball secondaries. Answer the following  What is provisional diagnosis  Discuss the etiopathogenesis  Describe the morphology  Mention the various para neoplastic syndromes produced by this lesion

3.A 50 years old man came with complaints of painless hematuria and pain in the right flank since one month and gave h/o loss of weight of about 10 Kg. in the last 6 months. O/E: A right sided flank mass is palpable on bimanual examination.  What is your diagnosis.  Explain the etiopathogenesis of the condition.  Describe the morphology of the lesion

1.Renal cell carcinoma

1.Name two microscopic subtypes of renal cell carcinoma

2.What is the genetic basis of Wilms tumor

3.Name four paraneoplastic syndromes with an example each for the underlying neoplasm causing it Answer in single sentence: (4x½=2)

4.Nephroblastoma

5.What is paraneoplastic syndrome

1.Risk factor associated with transitional cell carcinoma of urinary bladder is

• a) NSAID use
• b) Chronic smoking
• c) Chronic Alcoholism
• d) Urinary tract infections