Tubular & Interstitial Disease

1.A 10-year-old female presented with sudden onset of hematuria and oliguria. Urine examination shows presence of RBC, casts and mild proteinuria.

• a) What is your probable diagnosis
• b) Discuss etiopathogenesis and classification of the disease
• c) Mention the morphological features of the target organ
• d) Laboratory diagnosis of the disease

1.Pyelonephritis

2.Obstructive uropathy

1.Urinary casts

2.Microscopic examination of urine

3.Nephrotic range proteinuria – Definition and common causes

1.Name the mode of inheritance of Adult Polycystic Kidney Disease

2.Enumerate two causes of proteinuria

3.Proteinuria – causes and two tests for detection

4.Name the most common forms of autosomal recessive polycystic kidney disease

5.Causes of heavy proteinuria

6.Gross features of adult polycystic kidney

7.List two urinary casts